SkinSelf Renewal Blog, Weight Loss
Retatrutide vs Tirzepatide (Zepbound): Which Weight Loss Peptide Is Right for You?
Today, patients have more medical weight loss options than ever before. Because of this, many people ask the same question. “What is the difference between Retatrutide and Zepbound?” Both peptides are part of a new generation of metabolic therapies. However, they work in different ways. As a result, each option may be better suited for different patients. So, let’s break it down in a simple and patient-friendly way. Mechanism Comparison Although both peptides support appetite control and metabolic health, they work through different pathways. Tirzepatide (Zepbound) Tirzepatide is a dual-agonist peptide. In simple terms, it activates two metabolic receptors: • GLP-1• GIP Because of this dual action, Tirzepatide helps reduce appetite and improve insulin response at the same time. In addition, Tirzepatide is FDA-approved for medical weight loss. Clinical trials show average weight loss of approximately 20–21% under medical supervision. As a result, it has become one of the most…
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